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SCR130

Product Specifications

CAS Number

2377858-38-1

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

ClC1=CC=C (C=C1) C2CC (=NC23C (=O) NC (=S) NC3=O) C4=CC=C (Cl) C=C4

Molecular Formula

C19H13Cl2N3O2S

Additionnal Information

SCR130 is a novel DNA repair inhibitor with IC50s of 14 μM in Reh cells and 2 μM in Nalm6 cells. SCR130 specifically inhibits DNA Ligase IV‐mediated joining with minimal or no effect on Ligase III and Ligase I mediated joining.

Storage Conditions

3 years -20°C powder

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