Ciliobrevin D
Product Specifications
CAS Number
1370554-01-0
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
ClC1=CC (=C (C=C1) C (=O) C (\C#N) =C2/NC (=O) C3=CC=C (Cl) C=C3N2) Cl
Molecular Formula
C17H8Cl3N3O2
Additionnal Information
Ciliobrevin D (compound 5) is a cell-permeable, reversible and specific antagonist of AAA+ (ATPases associated with diverse cellular activities) ATPase motor cytoplasmic dynein. Ciliobrevin D perturbs primary cilia formation and blocks Hedgehog (Hh) signaling.
Storage Conditions
3 years -20°C powder
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