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Ciliobrevin D

Product Specifications

CAS Number

1370554-01-0

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

ClC1=CC (=C (C=C1) C (=O) C (\C#N) =C2/NC (=O) C3=CC=C (Cl) C=C3N2) Cl

Molecular Formula

C17H8Cl3N3O2

Additionnal Information

Ciliobrevin D (compound 5) is a cell-permeable, reversible and specific antagonist of AAA+ (ATPases associated with diverse cellular activities) ATPase motor cytoplasmic dynein. Ciliobrevin D perturbs primary cilia formation and blocks Hedgehog (Hh) signaling.

Storage Conditions

3 years -20°C powder

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