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Indisulam

Product Specifications

CAS Number

165668-41-7

Synonyms

E7070

Target

Carbonic Anhydrase

Applications

Metabolism

Smiles

N[S] (=O) (=O) C1=CC=C (C=C1) [S] (=O) (=O) NC2=C3[NH]C=C (Cl) C3=CC=C2

Molecular Formula

C14H12ClN3O4S2

Additionnal Information

Indisulam (E7070), a sulfonamide anticancer agent, is a potent carbonic anhydrase (CA) inhibitor that inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Indisulam suppresses the expression of cyclin E and phosphorylation of CDK2, both of which are essential for the G1 to S transition.

Storage Conditions

3 years -20°C powder

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