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BSO

Product Specifications

CAS Number

83730-53-4

Synonyms

L-Buthionine sulfoximine, l-BSO

Target

γGCS

Applications

Metabolism

Smiles

CCCC[S] (=N) (=O) CCC (N) C (O) =O

Molecular Formula

C8H18N2O3S

Additionnal Information

BSO is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase (γ-glutamylcysteine synthetase, γ-GCS) and depletes cellular glutathione levels. The IC50 of BSO on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

Storage Conditions

3 years -20°C powder

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