BSO
Product Specifications
CAS Number
83730-53-4
Synonyms
L-Buthionine sulfoximine, l-BSO
Target
γGCS
Applications
Metabolism
Smiles
CCCC[S] (=N) (=O) CCC (N) C (O) =O
Molecular Formula
C8H18N2O3S
Additionnal Information
BSO is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase (γ-glutamylcysteine synthetase, γ-GCS) and depletes cellular glutathione levels. The IC50 of BSO on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
Storage Conditions
3 years -20°C powder
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