SZL P1-41
Product Specifications
CAS Number
222716-34-9
Target
E3 Ligase
Applications
Ubiquitin
Smiles
CCC1=C (O) C (=C2OC=C (C (=O) C2=C1) C3=NC4=C (S3) C=CC=C4) CN5CCCCC5
Molecular Formula
C24H24N2O3S
Additionnal Information
SZL P1-41 (compound #25) is a specific inhibitor of S-phase kinase-associated protein 2 (Skp2) that indeed binds to Skp2, prevents Skp2-Skp1 interaction and inhibits Skp2 SCF E3 ligase activity, which consequently suppresses survival of cancer cells and cancer stem cells. SZL P1-41 causes higher apoptosis rates in cancer cells.
Storage Conditions
3 years -20°C powder
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