CDDO-Im (RTA-403)
Product Specifications
CAS Number
443104-02-7
Synonyms
CDDO-Imidazolide, TP-235
Target
Nrf2
Applications
NF-κB
Smiles
CC1 (C) CCC2 (CCC3 (C) C (C2C1) C (=O) C=C4C5 (C) C=C (C#N) C (=O) C (C) (C) C5CCC34C) C (=O) [N]6C=CN=C6
Molecular Formula
C34H43N3O3
Additionnal Information
CDDO-Im (RTA-403) is an activator of nuclear factor erythroid 2–related factor 2 (Nrf2) and peroxisome proliferator-activated receptor (PPAR) . CDDO-Im binds to PPARα and PPARγ with Ki of 232 nM and 344 nM, respectively. CDDO-Im inhibits inflammatory response and tumor growth in vivo.
Storage Conditions
3 years -20°C powder
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