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Lanraplenib (GS-SYK)

Product Specifications

CAS Number

1800046-95-0

Synonyms

GS-9876

Target

Syk

Applications

Protein Tyrosine Kinase

Smiles

NC1=CN=CC (=N1) C2=C[N]3C=CN=C3C (=N2) NC4=CC=C (C=C4) N5CCN (CC5) C6COC6

Molecular Formula

C23H25N9O

Additionnal Information

Lanraplenib (GS-SYK) is a potent, highly selective and orally active inhibitor of Spleen Tyrosine Kinase (SYK) with IC50 of 9.5 nM. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.

Storage Conditions

3 years -20°C powder

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