Tapinarof
Product Specifications
CAS Number
79338-84-4
Synonyms
GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505
Target
AhR
Applications
Immunology & Inflammation
Smiles
CC (C) C1=C (O) C=C (\C=C\C2=CC=CC=C2) C=C1O
Molecular Formula
C17H18O2
Additionnal Information
Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.
Storage Conditions
3 years -20°C powder
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