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BMS-986158

Product Specifications

CAS Number

1800340-40-2

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

C[N]1N=NC (=C1C2=CC3=C (N=C2) C4=C (C=C (C=C4) C (C) (C) O) [N]3C (C5CCOCC5) C6=CC=CC=C6) C

Molecular Formula

C30H33N5O2

Additionnal Information

BMS-986158 is a potent inhibitor of BET with IC50s of 6.6 nM and 5 nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively.

Storage Conditions

3 years -20°C powder

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