PROTAC SGK3 degrader-1

CC1=CC=C (F) C (=C1) [S] (=O) (=O) NC2=CC=C (C=C2) C3=NC4=C (C=N[NH]4) C (=N3) OCC5CN (CCCCCCOCCOCCOCC (=O) NC (C (=O) N6CC (O) CC6C (=O) NCC7=CC=C (C=C7) C8=C (C) N=CS8) C (C) (C) C) CCO5

PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC conjugate of the 308-R SGK inhibitor with the VH032 VHL binding ligand, targeting SGK3 (Serum/Glucocorticoid Regulated Kinase Family Member 3) for degradation.