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IFSP1

Product Specifications

CAS Number

150651-39-1

Target

Ferroptosis

Applications

Apoptosis

Smiles

CC1=CC=C (C=C1) C2=C (C3=NC4=CC=CC=C4N3C (=C2C#N) N) C#N

Molecular Formula

C20H13N5

Additionnal Information

IFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1/AIFM2) with EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout Pfa1 and HT1080 cells that overexpresses FSP1.Solutions are unstable and should be fresh-prepared.

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