What is the catalog number for Remibrutinib?

The catalog number for Remibrutinib is C14393-1g.

What sizes are available for Remibrutinib?

Remibrutinib is available in the following size(s): 1 g.

Is Remibrutinib in stock?

Remibrutinib is currently made to order / not held in immediate stock. Contact us for lead time.

Remibrutinib

Product Specifications

CAS Number

1787294-07-8

Synonyms

LOU064

Target

Interleukins

Applications

Immunology & Inflammation

Smiles

CC1=C (C=C (C=C1NC (=O) C2=C (C=C (C=C2) C3CC3) F) F) C4=C (C (=NC=N4) N) OCCN (C) C (=O) C=C

Molecular Formula

C27H27F2N5O3

Additionnal Information

Remibrutinib is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK) with IC50 of 1.3 nM, 2.5 nM and 18 nM for BTK, FcγR-induced IL8 and anti-IgM/IL4-induced CD69, respectively. Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases.