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UNC6852

Product Specifications

CAS Number

2688842-08-0

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=C (SC=N1) C2=CC=C (CNC (=O) C3CC (O) CN3C (=O) C (NC (=O) CCCNC (=O) C4=CC=C (C=C4) C5=CN=C (NCC6=CC=CO6) [N]7C=NN=C57) C (C) (C) C) C=C2

Molecular Formula

C43H48N10O6S

Additionnal Information

UNC6852 is a selective degrader that targets polycomb repressive complex 2 (PRC2) with IC50 of 247 nM for EED. UNC6852 is based on PROTAC and contains an EED226-derived ligand and a ligand for VHL.

Storage Conditions

3 years -20°C powder

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