BRD0705
Product Specifications
CAS Number
2056261-41-5
Target
GSK-3
Applications
PI3K/Akt/mTOR
Smiles
CCC1 (C2=CC=CC=C2) C3=CNNC3=NC4=C1C (=O) CC (C) (C) C4
Molecular Formula
C20H23N3O
Additionnal Information
BRD0705 is a potent, paralog selective and orally active inhibitor of GSK3α (Glycogen synthase kinase 3α) with IC50 of 66 nM and Kd of 4.8 μM. BRD0705 also inhibits GSK3β with IC50 of 515 nM. BRD0705 can be used for acute myeloid leukemia (AML) .
Storage Conditions
3 years -20°C powder
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