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Elzovantinib (TPX-0022)

Product Specifications

CAS Number

2271119-26-5

Synonyms

CSF1R-IN-2

Target

C-Met

Applications

Protein Tyrosine Kinase

Molecular Formula

C20H20FN7O2

Additionnal Information

Elzovantinib (TPX-0022, CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models.

Storage Conditions

3 years -20°C powder

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