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Amcenestrant (SAR439859)

Product Specifications

CAS Number

2114339-57-8

Target

Estrogen/progestogen Receptor

Applications

Endocrinology & Hormones

Smiles

C1CC2=C (C=CC (=C2) C (=O) O) C (=C (C1) C3=C (C=C (C=C3) Cl) Cl) C4=CC=C (C=C4) OC5CCN (C5) CCCF

Molecular Formula

C31H30Cl2FNO3

Additionnal Information

Amcenestrant (SAR439859, compound 43d) is an orally available and nonsteroidal selective estrogen receptor degrader (SERD) with potential antineoplastic activity. SAR439859 is a potent estrogen receptor (ER) antagonist with EC50 of 0.2 nM for ERα degradation.

Storage Conditions

3 years -20°C powder

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