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SB 265610

Product Specifications

CAS Number

211096-49-0

Target

CXCR

Applications

GPCR & G Protein

Smiles

BrC1=CC=CC=C1NC (=O) NC2=CC=C (C#N) C3=C2[NH]N=N3

Molecular Formula

C14H9BrN6O

Additionnal Information

SB265610, a competitive antagonist at the human CXCR2 receptor, can displace [125I]-IL-8 and [125I]-GROα with pIC50 values of 8.41 and 8.47 respectively, preventing receptor activation by binding to a region distinct from the agonist binding site.

Storage Conditions

3 years -20°C powder

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