Rotundic acid
Product Specifications
CAS Number
20137-37-5
Synonyms
Rutundic acid
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CC1CCC2 (CCC3 (C (=CCC4C3 (CCC5C4 (CCC (C5 (C) CO) O) C) C) C2C1 (C) O) C) C (=O) O
Molecular Formula
C30H48O5
Additionnal Information
Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways.
Storage Conditions
3 years -20°C powder
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