(+) -Isocorynoline
Product Specifications
CAS Number
475-67-2
Target
5-HT Receptor
Applications
Neuronal Signaling
Smiles
CN1CCC2=CC (=C (C3=C2C1CC4=C3C (=C (C=C4) OC) O) OC) OC
Molecular Formula
C20H23NO4
Additionnal Information
Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.
Storage Conditions
3 years -20°C powder
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