Giredestrant
Product Specifications
CAS Number
1953133-47-5
Synonyms
GDC-9545; RG6171
Target
Estrogen/progestogen Receptor
Applications
Endocrinology & Hormones
Smiles
CC1CC2=C (C (N1CC (CO) (F) F) C3=C (C=C (C=C3F) NC4CN (C4) CCCF) F) NC5=CC=CC=C25
Molecular Formula
C27H31F5N4O
Additionnal Information
Giredestrant (GDC-9545; RG6171) is an efficient and potent selective estrogen receptor degrader and a full antagonist with an IC50 of 0.05 nM in T-47D wild-type cells. It also exhibits anti-proliferative activity.
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