HQNO
Product Specifications
CAS Number
341-88-8
Synonyms
2-heptyl-4-hydroxyquinoline-N-oxide
Target
Others
Applications
Others
Smiles
CCCCCCCC1=CC (=O) C2=CC=CC=C2N1O
Molecular Formula
C16H21NO2
Additionnal Information
HQNO (2-heptyl-4-hydroxyquinoline-N-oxide) is a natural quinolone secreted by P. aeruginosa. HQNO is a potent inhibitor of the electron transport chain with Kd of 64 nM for the ubiquinol-ferricytochrome c oxidoreductase segment (Complex III) of the respiratory chain. HQNO is also an inhibitor of bacterial and mitochondrialType II NADH : quinone oxidoreductase (NDH-2) with IC50 of 7.3 μM in the presence of 50μM menadione.
Storage Conditions
3 years -20°C powder
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