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T-5224

Product Specifications

CAS Number

530141-72-1

Target

MMP

Applications

Proteases

Smiles

C1CCC (C1) OC2=CC (=C (C=C2) C (=O) C3=CC (=C (C=C3) OCC4=CC5=C (C=C4) C (=O) NO5) CCC (=O) O) O

Molecular Formula

C29H27NO8

Additionnal Information

T-5224 is a selective inhibitor of transcription factor c-Fos/activator protein (AP) -1 with anti-inflammatory effects. T-5224 specifically inhibits the DNA binding activity of c-Fos/c-Jun and the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription.

Storage Conditions

3 years -20°C powder

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