Actinomycin D (Dactinomycin)
Product Specifications
CAS Number
50-76-0
Synonyms
Act D, RASP-101
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Molecular Formula
C62H86N12O16
Additionnal Information
Actinomycin D (Dactinomycin, Act D, RASP-101) is a significant polypeptide antibiotic isolated from soil bacteria of the genus Streptomyces. Actinomycin D (Dactinomycin) inhibits DNA repair and rests the cell cycle at G1 phase with IC50 of 0.42 μM and 0.4 nM, respectively. Actinomycin D is an autophagy activator, induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive) . Please use it while wearing a protective face mask, gloves, and clothing.
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