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BRD3308

Product Specifications

CAS Number

1550053-02-5

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CC (=O) NC1=CC=C (C=C1) C (=O) NC2=C (C=C (C=C2) F) N

Molecular Formula

C15H14FN3O2

Additionnal Information

BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release.

Storage Conditions

3 years -20°C powder

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