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Alobresib (GS-5829)

Product Specifications

CAS Number

1637771-14-2

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=C (C (=NO1) C) C2=CC (=C3C (=C2) NC (=N3) C4CC4) C (C5=CC=CC=N5) (C6=CC=CC=N6) O

Molecular Formula

C26H23N5O2

Additionnal Information

Alobresib (GS-5829) is a novel BET inhibitor that represents a highly effective therapeutics agent against recurrent/chemotherapy-resistant USC-overexpressing c-Myc. Alobresib (GS-5829) inhibits CLL cell proliferation and induces leukemia cell apoptosis through deregulation of key signaling pathways, such as BLK, AKT, ERK1/2, and MYC. Alobresib (GS-5829) also inhibits NF-κB signaling.

Storage Conditions

3 years -20°C powder

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