What is the catalog number for BI-2852?

The catalog number for BI-2852 is C13818-100mg.

What sizes are available for BI-2852?

BI-2852 is available in the following size(s): 100 mg.

BI-2852 is currently made to order / not held in immediate stock. Contact us for lead time.

BI-2852

Product Specifications

CAS Number

2375482-51-0

Target

Ras

Applications

Apoptosis

Smiles

CN1C=C (N=C1) CN2C=CC3=C2C=C (C=C3) CNCC4=C (C5=CC=CC=C5N4) C6C7=C (C=CC (=C7) O) C (=O) N6

Molecular Formula

C31H28N6O2

Additionnal Information

BI-2852 is a potent inhibitor of KRAS that binds with nanomolar affinity to a pocket between switch I and II on RAS. BI-2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells.