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SRX3207

Product Specifications

CAS Number

2254693-15-5

Target

Syk

Applications

Protein Tyrosine Kinase

Smiles

CC1=NN (C=C1CN2CCC2) C3=NC (=NC=C3) NC4=CC=C (C=C4) C5=CSC6=C5OC (=CC6=O) N7CCOCC7

Molecular Formula

C29H29N7O3S

Additionnal Information

SRX3207 is an orally active dual inhibitor of Syk-PI3K with IC50 of 39.9 nM, 31200 nM, 3070 nM, 3070 nM, 244 nM, 388 nM, 9790 nM for Syk, Zap70, BRD41, BRD42, PI3K alpha, PI3K delta, PI3K gamma, respectively. SRX3207 blocks tumor immunosuppression and increases anti-tumor immunity.

Storage Conditions

3 years -20°C powder

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