BAY-985
Product Specifications
CAS Number
2409479-29-2
Target
TBK1
Applications
Immunology & Inflammation
Smiles
CC (C1=CC (=NC=C1) NC2=NC3=C (N2) C=C (C=C3) C4=CC (=NC=N4) N (C) C) N5CCN (CC5) C (=O) CC (F) (F) F
Molecular Formula
C27H30F3N9O
Additionnal Information
BAY-985 is a potent and highly selective TBK1/IKKε inhibitor. BAY-985 shows high potency toward TBK1 (IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKKε (IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM) .
Storage Conditions
3 years -20°C powder
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