Simurosertib
Product Specifications
CAS Number
1330782-76-7
Synonyms
TAK-931
Target
CDK
Applications
Cell Cycle
Smiles
CC1=C (C=NN1) C2=CC3=C (S2) C (=O) NC (=N3) C4CC5CCN4CC5
Molecular Formula
C17H19N5OS
Additionnal Information
Simurosertib (TAK-931), an oral cell division cycle 7 (CDC7) -selective inhibitor with an IC50<0.3 nM, induces S phase delay and replication stress and causes mitotic aberrations through centrosome dysregulation and chromosome missegregation, resulting in irreversible antiproliferative effects in cancer cells.
Storage Conditions
3 years -20°C powder
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