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MS1943

Product Specifications

CAS Number

2225938-17-8

Target

Histone Methyltransferase

Applications

Epigenetics

Smiles

CC1=CC (=C (C (=O) N1) CNC (=O) C2=C3C=NN (C3=CC (=C2) C4=CN=C (C=C4) N5CCN (CC5) CCNC (=O) CC67CC8CC (C6) CC (C8) C7) C (C) C) C

Molecular Formula

C42H54N8O3

Additionnal Information

MS1943 is an orally bioavailable EZH2 selective degrader that effectively reduces EZH2 levels in cells with IC50 of 120 nM for inhibiting EZH2 methyltransferase activity.

Storage Conditions

3 years -20°C powder

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