BI-3406
Product Specifications
CAS Number
2230836-55-0
Target
Ras
Applications
Apoptosis
Smiles
CC1=NC2=CC (=C (C=C2C (=N1) NC (C) C3=CC (=CC (=C3) N) C (F) (F) F) OC4CCOC4) OC
Molecular Formula
C23H25F3N4O3
Additionnal Information
BI-3406 (compound I-13) is a potent, selective and orally active inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with IC50 of 5 nM. BI-3406 reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 exhibits anti-tumor activities.
Storage Conditions
3 years -20°C powder
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