JHU395
Product Specifications
CAS Number
2079938-92-2
Target
Glutaminase
Applications
Proteases
Smiles
CC (C) OC (=O) C (CCC (=O) C=[N+]=[N-]) NC (=O) OC (OC (=O) C (C) (C) C) C1=CC=CC=C1
Molecular Formula
C22H29N3O7
Additionnal Information
JHU395 is a novel orally bioavailable GA (glutamine antagonists) prodrug designed to circulate inert in plasma, but permeate and release active GA within target tissues. JHU395 delivers active GA to malignant peripheral nerve sheath tumor (MPNST), and significantly inhibits tumor growth without observed toxicity.
Storage Conditions
2 years -20°C liquid
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