Adagrasib (MRTX849)
Product Specifications
CAS Number
2326521-71-3
Target
Ras
Applications
Apoptosis
Smiles
CN1CCCC1COC2=NC3=C (CCN (C3) C4=CC=CC5=C4C (=CC=C5) Cl) C (=N2) N6CCN (C (C6) CC#N) C (=O) C (=C) F
Molecular Formula
C32H35ClFN7O2
Additionnal Information
Adagrasib (MRTX849) is a potent, selective, and covalent KRASG12C inhibitor that exhibits favorable drug-like properties, selectively modifies mutant cysteine 12 in GDP-bound KRASG12C and inhibits KRAS-dependent signaling.
Storage Conditions
3 years -20°C powder
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