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Adagrasib (MRTX849)

Product Specifications

CAS Number

2326521-71-3

Target

Ras

Applications

Apoptosis

Smiles

CN1CCCC1COC2=NC3=C (CCN (C3) C4=CC=CC5=C4C (=CC=C5) Cl) C (=N2) N6CCN (C (C6) CC#N) C (=O) C (=C) F

Molecular Formula

C32H35ClFN7O2

Additionnal Information

Adagrasib (MRTX849) is a potent, selective, and covalent KRASG12C inhibitor that exhibits favorable drug-like properties, selectively modifies mutant cysteine 12 in GDP-bound KRASG12C and inhibits KRAS-dependent signaling.

Storage Conditions

3 years -20°C powder

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