ZT-12-037-01
Product Specifications
CAS Number
2328073-61-4
Target
Serine/threonin kinase
Applications
Cell Cycle
Smiles
CC (C) N1CCC (CC1) NC2=NC (=NC3=CC (=C (C=C32) OC) OC) NC4CC4
Molecular Formula
C21H31N5O2
Additionnal Information
ZT-12-037-01 is a specific and ATP-competitive STK19 inhibitor with IC50s of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N), respectively. It displays extremely high kinase selectivity using KINOMEscan against a panel of 468 diverse kinases using an in vitro ATP-site competition binding assay at 1 μM.
Storage Conditions
3 years -20°C powder
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