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ZT-12-037-01

Product Specifications

CAS Number

2328073-61-4

Target

Serine/threonin kinase

Applications

Cell Cycle

Smiles

CC (C) N1CCC (CC1) NC2=NC (=NC3=CC (=C (C=C32) OC) OC) NC4CC4

Molecular Formula

C21H31N5O2

Additionnal Information

ZT-12-037-01 is a specific and ATP-competitive STK19 inhibitor with IC50s of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N), respectively. It displays extremely high kinase selectivity using KINOMEscan against a panel of 468 diverse kinases using an in vitro ATP-site competition binding assay at 1 μM.

Storage Conditions

3 years -20°C powder

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