YKL-5-124
Product Specifications
CAS Number
1957203-01-8
Target
CDK
Applications
Cell Cycle
Smiles
CC1 (C2=C (CN1C (=O) NC (CN (C) C) C3=CC=CC=C3) C (=NN2) NC (=O) C4=CC=C (C=C4) NC (=O) C=C) C
Molecular Formula
C28H33N7O3
Additionnal Information
YKL-5-124 is a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for inhibiting CDK7/Mat1/CycH, CDK2 and CDK9 respectively. It displays biochemical and cellular selectivity for CDK7 over CDK12/13.
Storage Conditions
3 years -20°C powder
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