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Belvarafenib

Product Specifications

CAS Number

1446113-23-0

Synonyms

HM95573, GDC5573, RG6185

Target

Raf

Applications

MAPK

Smiles

CC1=C (C2=C (C=C1) C (=NC=C2) NC3=C (C (=CC=C3) Cl) F) NC (=O) C4=CSC5=C4N=CN=C5N

Molecular Formula

C23H16ClFN6OS

Additionnal Information

Belvarafenib is a selective and orally bioavailable pan-RAF kinase inhibitor with IC50 values of 41 nM, 7 nM and 2 nM for BRAF WT, BRAF (V600E) and CRAF kinases, respectively.

Storage Conditions

3 years -20°C powder

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