JH-RE-06
Product Specifications
CAS Number
1361227-90-8
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
CC (C) CC (=O) C1=C (NC2=C (C=CC (=C2C1=O) [N+] (=O) [O-]) Cl) NC3=C (C=C (C=C3) Cl) Cl
Molecular Formula
C20H16Cl3N3O4
Additionnal Information
JH-RE-06 is a potent REV1-REV7 interface inhibitor with an IC50 of 0.78 μM and Kd value of 0.42 μM, disrupting REV1-POL ζ-mediated mutagenic translesion synthesis (TLS) .
Storage Conditions
3 years -20°C powder
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