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Borussertib

Product Specifications

CAS Number

1800070-77-2

Target

Akt

Applications

PI3K/Akt/mTOR

Smiles

C=CC (=O) NC1=CC2=C (C=C1) NC (=O) N2C3CCN (CC3) CC4=CC=C (C=C4) C5=C (C=C6C (=N5) C=CNC6=O) C7=CC=CC=C7

Molecular Formula

C36H32N6O3

Additionnal Information

Borussertib is a covalent-allosteric inhibitor of protein kinase Akt with an IC50 of 0.8 nM and a Ki of 2.2 nM for WT Akt.

Storage Conditions

3 years -20°C powder

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