PF-06873600
Product Specifications
CAS Number
2185857-97-8
Target
CDK
Applications
Cell Cycle
Molecular Formula
C20H27F2N5O4S
Additionnal Information
PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (CDK2), CDK4, and CDK6 with Ki values of 0.1, 1.2, and 0.1 nM, respectively, blocks the phosphorylation of retinoblastoma protein (RB1), and limits the proliferation of OVCAR-3 ovarian cancer cells with EC50s of 19 and 45 nM, respectively.
Storage Conditions
3 years -20°C powder
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