PFK158

Product Specifications

CAS Number

1462249-75-7

Target

Autophagy

Applications

Autophagy

Smiles

C1=CC (=CC2=C1C=CC (=N2) C=CC (=O) C3=CC=NC=C3) C (F) (F) F

Molecular Formula

C18H11F3N2O

Additionnal Information

PFK158 is a potent and selective inhibitor of PFKFB3. It has improved PK properties and causes ~80% growth inhibition in several mouse models of human-derived tumors.

Storage Conditions

3 years -20°C powder

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