ML385

Product Specifications

CAS Number

846557-71-9

Target

Nrf2

Applications

NF-κB

Smiles

CC1=CC=CC=C1C (=O) N2CCC3=C2C=CC (=C3) C4=C (SC (=N4) NC (=O) CC5=CC6=C (C=C5) OCO6) C

Molecular Formula

C29H25N3O4S

Additionnal Information

ML385 is a novel and specific NRF2 inhibitor with an IC50 of 1.9 μM. It inhibits the downstream target gene expression of NRF2. NRF2 regulates the activity of several ferroptosis and lipid peroxidation-related proteins.

Storage Conditions

3 years -20°C powder

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