AZD3229
Product Specifications
CAS Number
2248003-60-1
Target
C-Kit
Applications
Protein Tyrosine Kinase
Smiles
CC (C) C1=CN (N=N1) CC (=O) NC2=CC=C (C=C2) NC3=NC=NC4=C3C (=CC (=C4) OCCOC) F
Molecular Formula
C24H26FN7O3
Additionnal Information
AZD3229 is a potent, pan-Kit (c-Kit) mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant Kit (c-Kit) driven Ba/F3 cell lines (GI50=1-50 nM), with good margin to KDR-driven effects. It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V) .
Storage Conditions
3 years -20°C powder
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