LY 3200882
Product Specifications
CAS Number
1898283-02-7
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CC (C) (C1=NC=CC (=C1) NC2=NC=CC (=C2) OC3=CN (N=C3C4CCOCC4) C5CC5) O
Molecular Formula
C24H29N5O3
Additionnal Information
LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI) . It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.
Storage Conditions
3 years -20°C powder
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