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Tinostamustine (EDO-S101)

Product Specifications

CAS Number

1236199-60-2

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CN1C2=C (C=C (C=C2) N (CCCl) CCCl) N=C1CCCCCCC (=O) NO

Molecular Formula

C19H28Cl2N4O2

Additionnal Information

Tinostamustine (EDO-S101) is a first-in-class alkylating deacetylase inhibitor with IC50 values of 9 nM, 9 nM, 25 nM and 107 nM for HDAC1, HDAC2, HDAC3 and HDAC8 (Class 1 HDACs) respectively and 6 nM, 72 nM for HDAC6 and HDAC10 (Class II HDACs) .

Storage Conditions

3 years -20°C powder

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