Tinostamustine (EDO-S101)
Product Specifications
CAS Number
1236199-60-2
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CN1C2=C (C=C (C=C2) N (CCCl) CCCl) N=C1CCCCCCC (=O) NO
Molecular Formula
C19H28Cl2N4O2
Additionnal Information
Tinostamustine (EDO-S101) is a first-in-class alkylating deacetylase inhibitor with IC50 values of 9 nM, 9 nM, 25 nM and 107 nM for HDAC1, HDAC2, HDAC3 and HDAC8 (Class 1 HDACs) respectively and 6 nM, 72 nM for HDAC6 and HDAC10 (Class II HDACs) .
Storage Conditions
3 years -20°C powder
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