DBET6
Product Specifications
CAS Number
1950634-92-0
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) NCCCCCCCCNC (=O) COC4=CC=CC5=C4C (=O) N (C5=O) C6CCC (=O) NC6=O) C7=CC=C (C=C7) Cl) C
Molecular Formula
C42H45ClN8O7S
Additionnal Information
DBET6 is a highly cell-permeable PROTAC degrader of BET bromodomains with an IC50 of 14 nM for BRD4 binding. dBET6 also induces c-MYC downregulation and apoptosis.
Storage Conditions
3 years -20°C powder
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